Teams abounded throughout the 1920s. There were hundreds of men's professional basketball teams in towns and cities all over the United States, and little organization of the professional game. Players jumped from team to team and teams played in armories and smoky dance halls. Leagues came and went. Barnstorming squads such as the Original Celtics and two all-African American teams, the New York Renaissance Five ("Rens") and the (still existing) Harlem Globetrotters played up to two hundred games a year on their national tours.

In 1946, the Basketball Association of America (BAA) was formed. The first game was played in Toronto, Ontario, Canada between the Toronto Huskies and New York Knickerbockers on November 1, 1946. Three seasons later, in 1949, the BAA merged with the National Basketball League (NBL) to form the National Basketball Association (NBA). By the 1950s, basketball had become a major college sport, thus paving the way for a growth of interest in professional basketball. In 1959, a basketball hall of fame was founded in Springfield, Massachusetts, site of the first game. Its rosters include the names of great players, coaches, referees and people who have contributed significantly to the development of the game. The hall of fame has people who have accomplished many goals in their career in basketball. An upstart organization, the American Basketball Association, emerged in 1967 and briefly threatened the NBA's dominance until the ABA-NBA merger in 1976. Today the NBA is the top professional basketball league in the world in terms of popularity, salaries, talent, and level of competition.


Diamond DeShields (#1) drives to the basket around Maya Moore (#23) in the Minnesota Lynx vs Chicago Sky game
The NBA has featured many famous players, including George Mikan, the first dominating "big man"; ball-handling wizard Bob Cousy and defensive genius Bill Russell of the Boston Celtics; charismatic center Wilt Chamberlain, who originally played for the barnstorming Harlem Globetrotters; all-around stars Oscar Robertson and Jerry West; more recent big men Kareem Abdul-Jabbar, Shaquille O'Neal, Hakeem Olajuwon and Karl Malone; playmakers John Stockton, Isiah Thomas and Steve Nash; crowd-pleasing forwards Julius Erving and Charles Barkley; European stars Dirk Nowitzki, Pau Gasol and Tony Parker; Latin American stars Manu Ginobili, more recent superstars, Allen Iverson, Kobe Bryant, Tim Duncan, LeBron James, Stephen Curry, Giannis Antetokounmpo, etc.; and the three players who many credit with ushering the professional game to its highest level of popularity during the 1980s and 1990s: Larry Bird, Earvin "Magic" Johnson, and Michael Jordan.

In 2001, the NBA formed a developmental league, the National Basketball Development League (later known as the NBA D-League and then the NBA G League after a branding deal with Gatorade). As of the 2023–24 season, the G League has 31 teams.